Fellow Story

Vogel quoted in Washington post article about how BPA still everywhere, mounting evidence suggests harmful effects

When chemicals such as BPA mimic hormones, it leads to what’s called endocrine disruption. “The effect is not necessarily toxic in the traditional sense,” says Sarah Vogel, director of the health program at the Environmental Defense Fund and author of “Is it Safe? BPA and the Struggle to Define the Safety of Chemicals,” but it is a disruption.

Hormonal signals work the way a lock and key work. We have receptors (the locks) that receive signals from hormones (the keys). “[BPA] is almost like a little master key because it can fit into many of these little locks that are in your body and in your cells,” says Emilie Rissman, a behavioral neuroendocrinologist at the University of Virginia.

Rissman and other researchers are finding that when humans and other animals are exposed to BPA during critical developmental windows such as in the womb and in infancy, the chemical can scramble cellular signals and leave lasting biological effects.

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