Mohawk midwife Katsi Cook lives in Akwesasne, an indigenous community in upstate New York that is downwind and downstream from three Superfund sites. For years she witnessed elevated rates of miscarriages, birth defects, and cancer in her town, ultimately drawing connections between environmental contamination and these maladies. When she brought her findings to environmental health researchers, Cook sparked the United States’ first large-scale community-based participatory research project.