While the practice of biodiversity conservation has matured over the past decade, decisions for proposed actions still commonly lack evidence-based and return on investment (ROI) frameworks. That picture, however, is beginning to change. Planners and practitioners are beginning to embrace operating frameworks similar to the “effectiveness revolution” in public health. Relatedly, rather than ignoring the economics of conservation practice, planners and practitioners are adopting approaches that incorporate the costs of interventions into prioritizations.